{"id":4047,"date":"2023-01-31T11:56:45","date_gmt":"2023-01-31T17:56:45","guid":{"rendered":"https:\/\/nuevo22.cidsamexico.com\/?post_type=al_product&p=4047"},"modified":"2023-01-31T12:10:07","modified_gmt":"2023-01-31T18:10:07","slug":"mitolite-nir-fx690","status":"publish","type":"al_product","link":"https:\/\/nuevo22.cidsamexico.com\/index.php\/productos\/mitolite-nir-fx690\/","title":{"rendered":"MitoLite\u2122 NIR FX690"},"content":{"rendered":"\n

Las mitocondrias son org\u00e1nulos encerrados en una membrana que se encuentran en la mayor\u00eda de las c\u00e9lulas eucariotas. Las mitocondrias generan la mayor parte del suministro celular de ATP. Adem\u00e1s de suministrar energ\u00eda celular, las mitocondrias participan en una serie de otros procesos, como la se\u00f1alizaci\u00f3n, la diferenciaci\u00f3n celular, la muerte celular, as\u00ed como el control del ciclo celular y el crecimiento celular. Las mitocondrias se han implicado en varias enfermedades humanas, incluidos los trastornos mitocondriales y la disfunci\u00f3n card\u00edaca, y pueden desempe\u00f1ar un papel en el proceso de envejecimiento. <\/p>\n\n\n\n

Mitolite\u2122 NIR FX690 est\u00e1 dise\u00f1ado para marcar mitocondrias en c\u00e9lulas vivas con fluorescencia infrarroja cercana. Se acumula selectivamente en las mitocondrias probablemente a trav\u00e9s del gradiente de potencial de membrana mitocondrial. Es una opci\u00f3n ideal para obtener im\u00e1genes de c\u00e9lulas vivas y tejidos donde el fondo bajo y la alta relaci\u00f3n se\u00f1al-ruido son cr\u00edticos. Este indicador mitocondrial fluorescente se retiene en las mitocondrias durante mucho tiempo ya que lleva un grupo de retenci\u00f3n celular. Esta caracter\u00edstica clave aumenta significativamente la eficacia de la tinci\u00f3n. Es \u00fatil para una variedad de estudios, incluida la adhesi\u00f3n celular, la quimiotaxis, la resistencia a m\u00faltiples f\u00e1rmacos, la viabilidad celular, la apoptosis y la citotoxicidad.<\/p>\n\n\n\n

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Catalogo<\/th>Producto<\/th>Presentaci\u00f3n<\/th><\/tr><\/thead>
AAT-22690<\/td>MitoLite\u2122 NIR FX690<\/td>500 pruebas<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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SDS<\/a><\/p>\n\n\n\n

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Protocol<\/a><\/p>\n<\/div>\n\n\n\n

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Importante: Solo para uso en investigaci\u00f3n (RUO). Almacenamiento: Congelar (< -15 \u00b0C); Minimizar la exposici\u00f3n a la luz.<\/p>\n\n\n\n

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Espectro<\/mark><\/p>\n\n\n\n

Abrir en Advanced Spectrum Viewer<\/a><\/em><\/p>\n\n\n\n

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Propiedades espectrales<\/mark><\/p>\n\n\n\n

Exitaci\u00f3n<\/td>658<\/td><\/tr>
Emisi\u00f3n<\/td>691<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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Imagen<\/mark><\/p>\n\n\n\n

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Figura 1.<\/strong> Im\u00e1genes de fluorescencia de c\u00e9lulas HeLa te\u00f1idas con MitoLite\u2122 NIR FX690 utilizando un microscopio de fluorescencia con un juego de filtros Cy5 (rojo). Despu\u00e9s de la fijaci\u00f3n, las c\u00e9lulas se marcaron con tinte de actina F iFluor\u00ae 488-Phalloidin (Cat\u00e1logo 23115, verde) y se contrastaron con Nuclear Blue\u2122 DCS1 (Cat\u00e1logo 17548, azul).<\/p>\n\n\n\n

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MitoLite\u2122 Red CMXRos<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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Bibliograf\u00eda<\/mark><\/p>\n\n\n\n

Co-delivery of VP-16 and Bcl-2-targeted antisense on PEG-grafted oMWCNTs for synergistic in vitro anti-cancer effects in non-small and small cell lung cancer<\/a>
Authors: <\/strong>Heger, Zbynek and Polanska, Hana and Krizkova, Sona and Balvan, Jan and Raudenska, Martina and Dostalova, Simona and Moulick, Amitava and Masarik, Michal and Adam, Vojtech
Journal: <\/strong>Colloids and Surfaces B: Biointerfaces (2017): 131–140<\/p>\n\n\n\n

Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin<\/a>
Authors: <\/strong>Lv, Xin and Song, Dong-mei and Niu, Ying-hao and Wang, Bao-shan
Journal: <\/strong>Apoptosis (2016): 489–501<\/p>\n\n\n\n

Effective two-photon excited photodynamic therapy of xenograft tumors sensitized by water-soluble bis (arylidene) cycloalkanone photosensitizers<\/a>
Authors: <\/strong>Zou, Qianli and Zhao, Hongyou and Zhao, Yuxia and Fang, Yanyan and Chen, Defu and Ren, Jie and Wang, Xiaopu and Wang, Ying and Gu, Ying and Wu, Feipeng
Journal: <\/strong>Journal of medicinal chemistry (2015): 7949–7958<\/p>\n\n\n\n

Melatonin promotes adipogenesis and mitochondrial biogenesis in 3T3-L1 preadipocytes<\/a>
Authors: <\/strong>Kato, Hisashi and Tanaka, Goki and Masuda, Shinya and Ogasawara, Junetsu and Sakurai, Takuya and Kizaki, Takako and Ohno, Hideki and Izawa, Tetsuya
Journal: <\/strong>Journal of Pineal Research (2015): 267–275<\/p>\n\n\n\n

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Referencias<\/mark><\/p>\n\n\n\n

Ver todas las 70 referencias: Citation Explorer<\/a><\/em><\/p>\n\n\n\n

Quantification of carbonylated proteins in rat skeletal muscle mitochondria using capillary sieving electrophoresis with laser-induced fluorescence detection
Authors: <\/strong>Feng J, Arriaga EA.
Journal: <\/strong>Electrophoresis (2008): 475<\/p>\n\n\n\n

Calcium, mitochondria and apoptosis studied by fluorescence measurements
Authors: <\/strong>Roy SS, Hajnoczky G.
Journal: <\/strong>Methods (2008): 213<\/p>\n\n\n\n

Fluorescence imaging of mitochondria in yeast
Authors: <\/strong>Swayne TC, Gay AC, Pon LA.
Journal: <\/strong>Methods Mol Biol (2007): 433<\/p>\n\n\n\n

A fluorescence assay for peptide translocation into mitochondria
Authors: <\/strong>Martinez-Caballero S, Peixoto PM, Kinnally KW, Campo ML.
Journal: <\/strong>Anal Biochem (2007): 76<\/p>\n\n\n\n

Fast electrophoretic analysis of individual mitochondria using microchip capillary electrophoresis with laser induced fluorescence detection
Authors: <\/strong>Duffy CF, MacCraith B, Diamond D, O’Kennedy R, Arriaga EA.
Journal: <\/strong>Lab Chip (2006): 1007<\/p>\n\n\n\n

Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer
Authors: <\/strong>Elmore SP, Nishimura Y, Qian T, Herman B, Lemasters JJ.
Journal: <\/strong>Arch Biochem Biophys (2004): 145<\/p>\n\n\n\n

A fluorescence-based technique for screening compounds that protect against damage to brain mitochondria
Authors: <\/strong>Kristian T, Fiskum G.
Journal: <\/strong>Brain Res Brain Res Protoc (2004): 176<\/p>\n\n\n\n

Determination of the cardiolipin content of individual mitochondria by capillary electrophoresis with laser-induced fluorescence detection
Authors: <\/strong>Fuller KM, Duffy CF, Arriaga EA.
Journal: <\/strong>Electrophoresis (2002): 1571<\/p>\n\n\n\n

Fluorescence imaging of metabolic responses in single mitochondria
Authors: <\/strong>Nakayama S, Sakuyama T, Mitaku S, Ohta Y.
Journal: <\/strong>Biochem Biophys Res Commun (2002): 23<\/p>\n\n\n\n

Visualisation of mitochondria in living neurons with single- and two-photon fluorescence laser microscopy
Authors: <\/strong>Dedov VN, Cox GC, Roufogalis BD.
Journal: <\/strong>Micron (2001): 653<\/p>\n\n\n\n

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Application notes (en Ingles)<\/mark><\/p>\n\n\n\n

A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells<\/a>
Abbreviation of Common Chemical Compounds Related to Peptides<\/a>
Annexin V<\/a>
Bright Tide Fluor\u2122-Based Fluorescent Peptides and Their Applications In Drug Discovery and Disease Diagnosis<\/a>
Calcein<\/a><\/p>\n\n\n\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Este indicador mitocondrial es \u00fatil para una variedad de estudios, incluida la adhesi\u00f3n celular, la quimiotaxis, la resistencia a m\u00faltiples f\u00e1rmacos, la viabilidad celular, la apoptosis y la citotoxicidad.<\/p>\n","protected":false},"featured_media":4042,"template":"","al_product-cat":[34],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/al_product\/4047"}],"collection":[{"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/al_product"}],"about":[{"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/types\/al_product"}],"version-history":[{"count":2,"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/al_product\/4047\/revisions"}],"predecessor-version":[{"id":4051,"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/al_product\/4047\/revisions\/4051"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/media\/4042"}],"wp:attachment":[{"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/media?parent=4047"}],"wp:term":[{"taxonomy":"al_product-cat","embeddable":true,"href":"https:\/\/nuevo22.cidsamexico.com\/index.php\/wp-json\/wp\/v2\/al_product-cat?post=4047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}